Three NCI-funded Cloud Resources (CRs), each with distinct capabilities, make CRDC data accessible through their platforms, without the cost or complexity of downloading regularly updated data to a local compute environment.
Researchers typically use secure workspaces within one of the Cloud Resources for individual or collaborative exploration and analytic work, taking advantage of the cloud’s elastic compute capabilities and the analytical tools. Users can upload their own data to the secure cloud environment for comparative analysis with NCI-funded datasets.
Through the CRs, users have access to thousands of publicly available tools – analytical applications and workflows – that can be tailored for specific projects. Additionally, users can bring their own proprietary tools to their secure cloud workspace.
| Each of the NCI-funded cloud resources has unique capabilities. | |
|---|---|
 | Broad Institute FireCloud (FC) Focused on running production pipelines Based on the Google Cloud Platform (GCP) |
 | ISB Cancer Gateway in the Cloud (ISB-CGC) Focused on Command-line savvy users, Big Query, and Specialty Databases Based on the Google Cloud Platform (GCP) |
 | Seven Bridges Cancer Genomics Cloud, powered by Velsera (SB-CGC) Focused on non-technical users with interface & visual displays Based on the Amazon Web Services (AWS) platform |
Cloud Resources Make Datasets Accessible
The CRDC CRs make data from various programs and initiatives accessible. Below is an outline of the most used datasets and where they can be found.
| Data Commons | Datasets | FC | ISB | SB |
|---|---|---|---|---|
| TCGA (The Cancer Genome Atlas) |  | | |
| TARGET (Therapeutically Applicable Research to Generate Effective Treatments) | | | | |
| APOLLO | | | | |
| CPTAC | | | | |
| CPTAC (Clinical Proteomic Tumor Analysis Consortium) | | | |
| APOLLO (applied Proteomics Organizational Learning and Outcomes) | | | | |
| ICPC (International Cancer Proteogenomic Consortium) | | | | |
| CBTN (Children’s Brain Tumor Network) | | | | |
| ICDC | CMPC (The Comparative Molecular Characterization Program) | | ||
| COP (Comparative Oncology Program) | | |||
| PCCR The Purdue University Center for Cancer Research) | | |||
| CDS | PPTC (Pediatric Preclinical Testing consortium) | | ||
| HTAN (Human Tumor Atlas Network) | | | | |
| CCDI (Childhood Cancer Data Initiative) | | |||
| IDC | TCGA (The Cancer Genome Atlas) | | ||
| CTDC | CMB (Cancer Moonshot Biobank) | |